Buddhadeb was born and raised in Insura-Hooghly, West Bengal. He obtained his B.Sc. (2001) in chemistry from the Burdwan University and M.Sc. (2003) in chemistry from Visva-Bharati University. In 2003, he left Visva-Bharati and enrolled in Kalyani University for his Ph.D. in the laboratories of Professor K. C. Majumdar. In 2009, he accepted a postdoctoral research associateship from the University of Illinois at Chicago, USA in the group of Professor Vladimir Gevorgyan.

Spending two years at Chicago, he then moved to the Michigan State University, Michigan, USA for his next postdoctoral research program in the laboratories of Professor Milton R. Smith III. Group (2011-July 2014). In August 2014, he moved to the Centre of Bio-Medical Research (CBMR) Lucknow, India as a DST-Ramanujan Fellow to start his independent research career. In November 2016, he joined as an Assistant Professor and promoted to Associate Professor in November 2019. His research interest includes the catalyst/ligand engineering for the C–H bond activation/functionalization, especially C–H bond borylations of organic molecules and metal-nitrene/carbene chemistry by means of denitrogenative transformations to make high-valued nitrogen heterocycles.

• Research Interests:

  • Transition metal-mediated C–H bond activation/functionalization via noncovalent interactions
  • Development of new synthetic methodologies and drug discovery
  • Design and synthesis of new ligands and catalytic systems for organic reactions
  • Organometallics, especially organo-boron and organo-silicon chemistry
  • Metal-nitrene/carbene chemistry

1. Transition Metal-Catalyzed Denitrogenative Annulation to Access High-Valued N-Heterocycles. Das, S. K.; Roy, S.; Chattopadhyay, B. Angew. Chem. Int. Ed. 2023, 62, e202210912. [Link]
   

   Click here for more

2. Iron-Catalyzed Intermolecular Amination of Benzylic C(sp3)–H Bonds. Khatua, H.; Das, S.; Patra, S.; Das, S. K.; Roy, S.; Chattopadhyay, B. J. Am. Chem. Soc. 2022, 144, 21858–21866.

   Click here for more

3. Metal-Catalysed C–H Bond Activation and Borylation. Bisht, R.; Haldar, C.; Hassan, M. M. M.; Hoque, E. M.; Chaturvedi, J.; Chattopadhyay, B. Chem. Soc. Rev. 2022, 51, 5042-5100.

   Click here for more

4. Iridium-Catalyzed Ligand-Controlled Remote para-Selective C–H Activation and Borylation of Twisted Aromatic Amides. Hoque, E. M.; Bisht, R.; Unnikrishnan, A.; Dey, S.; Hassan, M. M. M.; Guria, S.; Rai, R. N.; Sunoj, R. B.; Chattopadhyay, B. Angew. Chem. Int. Ed. 2022, 61, e202203539.

   Click here for more

5. Road Map for the Construction of High-Valued N-Heterocycles via Denitrogenative Annulation. Roy, S.; Das, S. K.; Khatua, H.; Das, S.; Chattopadhyay, B. Acc. Chem. Res. 2021, 54, 4395–4409.

   Click here for more

6. Meta Selective C–H Borylation of Sterically Biased and Unbiased Substrates Directed by Electrostatic Interaction. Chaturvedi, J.; Haldar, C.; Bisht, R.; Pandey, G.; Chattopadhyay, B. J. Am. Chem. Soc. 2021, 143, 7604-7611.

   Click here for more

7. Remarkably Efficient Iridium Catalysts for Directed C(sp2)−H and C(sp3)−H Borylation of Diverse Classes of Substrates. Hoque, E.; Hassan, M. M. M.; Chattopadhyay, B. J. Am. Chem. Soc. 2021, 143, 5022–5037.

   Click here for more

8. Iron‐Catalyzed Radical Activation Mechanism for Denitrogenative Rearrangement Over C(sp3)–H Amination. Roy, S.; Das, S. K.; Khatua, H.; Das, S.; Singh, K. N.; Chattopadhyay, B. Angew. Chem. Int. Ed. 2021, 60, 8772-8780.

   Click here for more

9. Dual Reactivity of 1,2,3,4‐Tetrazole: Manganese‐Catalyzed Click Reaction and Denitrogenative Annulation. Hillol Khatua, Sandip Kumar Das, Satyajit Roy, Chattopadhyay, B. Angew. Chem. Int. Ed. 2021, 60, 304-312.

   Click here for more

10. Iron-Catalyzed Amination of Strong Aliphatic C(sp3)–H Bonds. Sandip Kumar Das, Satyajit Roy, Hillol Khatua, Chattopadhyay, B. J. Am. Chem. Soc. 2020, 142, 16211-16217.

    Click here for more

11. Iron(II)‐Based Metalloradical Activation: Switch from Traditional Click Chemistry to Denitrogenative Annulation. Roy, S.; Khatua, H.; Das, S. K.; Chattopadhyay, B. Angew. Chem. Int. Ed. 2019, 58, 11439-11443.

    Click here for more

12. Amide Effect in C–H Activation: Noncovalent Interactions with L‐Shaped Ligand for meta Borylation of Aromatic Amides. Bisht, R.; Hoque, E.; Chattopadhyay, B. Angew. Chem. Int. Ed. 2018, 57, 15762-15766

    Click here for more

13. Ir-Catalyzed Intramolecular Transannulation/C(sp2)–H Amination of 1,2,3,4-Tetrazoles by Electrocyclization. Das, S. K.; Roy, S.; Khatua, H.; Chattopadhyay, B. J. Am. Chem. Soc. 2018, 140, 8429-8433.

    Click here for more

14. Cobalt(II)-Based Metalloradical Activation of 2-(Diazomethyl)pyridines for Radical Transannulation and Cyclopropanation. Roy, S.; Das, S. K.; Chattopadhyay, B. Angew. Chem. Int. Ed. 2018, 57, 2238-2243.

    Click here for more

15. Noncovalent Interactions in Ir-Catalyzed C–H Activation: L-Shaped Ligand for Para-Selective Borylation of Aromatic Esters. Hoque, E.; Bisht, R.; Haldar, C.; Chattopadhyay, B. J. Am. Chem. Soc. 2017, 139, 7745-7748.

    Click here for more

16. Ir-Catalyzed Ortho Borylation of Phenols Directed by Substrate-Ligand Electrostatic Interactions: A Combined Experimental/in Silico Strategy for Optimizing Weak Interactions. Chattopadhyay, B.; Dannatt, J. E.; Sanctis, I. L. A.-de.; Gore, K. A.; Maleczka, R. E.; Singleton, D. A.; Smith, M. R. J. Am. Chem. Soc. 2017, 139, 7864-7871.

    Click here for more

17. Formal Ir-Catalyzed Ligand-Enabled Ortho- and Meta-Borylation of Aromatic Aldehydes via in Situ Generated Imines. Bisht, R.; Chattopadhyay, B. J. Am. Chem. Soc. 2016, 138, 84-87.

    Click here for more